LEHRSTUHL FÜR

SYSTEMBIOLOGIE

Decoding cellular communication - an information theoretic perspective on cytokine and endocrine signaling
In: Current opinion in endocrine and metabolic research - Amsterdam: Elsevier . - 2022

The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling
In: Cell communication and signaling - London: Biomed Central, Bd. 19 (2021), 1, insges. 19 S.

Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis
In: Liver international: official journal of the International Association for the Study of the Liver - Oxford: Wiley-Blackwell, 2003, Bd. 40.2020, 9, S. 2172-2181

Intragenic regulation of SOCS3 isoforms
In: Cell communication and signaling - London: Biomed Central, Volume 17 (2019), 1, Artikel 70, insgesamt 15 Seiten

Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression - fusing experimental insights and dynamic modelling
In: Cell communication and signaling - London: Biomed Central, Vol. 17.2019, 1, Art. 17:46, insgesamt 21 Seiten

Robustness and information transfer within IL-6-induced JAK/STAT signalling
In: Communications biology - London: Springer Nature, Vol. 2.2019, Art. 27, insgesamt 14 S.

Quantitative proteomics and systems analysis of cultured H9C2 cardiomyoblasts during differentiation over time supports a function follows form model of differentiation
In: Molecular omics: research in proteomics, transcriptomics, metabolomics and other omics sciences - Cambridge: Royal Society of Chemistry, 2018

Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-Inhibitor REDD1 in a STAT3-dependent manner
In: Cellular signalling - Amsterdam [u.a.]: Elsevier Science, 1989, Bd. 28.2016, 8, S. 907-916

A two-level approach for fusing early signaling events and long term cellular responses
In: IFAC-PapersOnLine/ Internationale Förderung für Automatische Lenkung - Frankfurt: Elsevier, 2015, Bd. 48.2015, 8, S. 1228-1233

Systems biology of IL-6, IL-12 family cytokines
In: Cytokine & growth factor reviews - Amsterdam [u.a.]: Elsevier Science, Bd. 26.2015, 5, S. 595-602

JAK/STAT signalling - an executable model assembled from molecule-centred modules demonstrating a module-oriented database concept for systems and synthetic biology
In: Molecular BioSystems - Cambridge: Royal Society of Chemistry, 2005, Bd. 9.2013, S. 1290-1307

Determination of protein turnover rates in the JAK/STAT pathway using a radioactive pulse-chase approach
In: JAK-STAT signalling: methods and protocols / ed. by Sandra E. Nicholson and Nicos A. Nicola: methods and protocols - New York [u.a.]: Humana Pr., 2013 . - 2013, S. 69-80 - (Methods in molecular biology; 967)

JAK-STAT signalling as example for a database-supported modular modelling concept
In: Gilbert, David: : Computational Methods in Systems Biology. - Berlin : Springer, S. 362-365, 2012 - (Lecture Notes in Bioinformatics; 7605)

Glucocorticoids increase interleukin-6 dependent gene induction by interfering with the expression of the SOCS 3 feedback inhibitor
In: Hepatology. - Hoboken, NJ : Wiley Interscience, Bd. 55.2012, 1, S. 256-266

Interleukin-6 signalling - more than Jaks and STATs
In: European journal of cell biology. - Amsterdam : Elsevier, Bd. 91.2012, 6/7, S. 486-495

Model-driven experimental analysis of the function of SHP-2 in IL-6-induced Jak/STAT signaling
In: Molecular BioSystems. - Cambridge : Royal Society of Chemistry, 8, S. 2119-2134, 2012

A simple work flow for biologically inspired model reduction - application to early JAK-STAT signaling
In: BMC systems biology - London: BioMed Central, Bd. 5.2011, 30, insges. 30 S.

Glucagon counteracts interleukin-6-dependent gene expression by redundant action of EPAC and PKA
In: Biological chemistry - Berlin [u.a.]: de Gruyter, Bd. 392.2011, S. 1123-1134